Comparative study belween plant extracts (Caesalpinia paraguariensis) with antibacterial activity and synthetic antibiotics of frequent application in antiinfection therapy

SGARIGLIA, M.A.; SOBERÓN, J.R.; QUIROGA, E.N.; VATTUONE, M.A.

Tucumán (Argentina)

Congreso; XXII Annual Meeting of Tucuman Biology Society; 2005

Tucuman Biology Society (publicado en Bio Cell 30 (1))

The aim of this study was the evaluation of the in vitro antibacterial activity of Caesalpinia paraguariensis extracts (Infusion, Decoction and Tincture) against 22 bacteria. This activity was compared with that of synthetic antibiotics. Synthetic drugs: Amoxicillin and Ciprofloxacin, were chosen taking into consideration their antibacterial spectrum, action mode and mechanisms, theirs frequency of use as therapeutic indication. Streptomycin sulphate, an ample spectrum antibiotic, was employed to compare the plant pathogenic action. We determined MICs and MBCs by broth microdilution method, and agar dilution method respectively (Muller Hinton medium). Although plant extracts and synthetic drug MICs and MBCs are not comparable from a quantitative point of view, some strains were sensible to the assayed extracts and simultaneously resistant to synthetic antibiotics. Moreover, we will use them as reference in the bioactivity-guided purification process.