Successful management with fosfomycin/ceftazidime of an infection caused by multiple highly related subtypes of MDR and XDR KPC-producing Serratia marcescens

RODRÍGUEZ, CECILIA; BRENGI, SILVINA; CÁCERES, MARIEL AGUSTINA; MOCHI, SILVANA; VIÑAS, MARÍA ROSA; RIZZA, CONSTANZA ANTICH; MERLETTI, GRACIELA; BRU, ELENA; ASSA, JOSÉ DANIEL; RAYA, RAÚL RICARDO; CENTRÓN, DANIELA

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

ELSEVIER SCIENCE BV

Año: 2018

0924-8579

Multidrug (MDR) and extensively drug resistant (XDR) S. marcescens infections are increasing in several hospital wards around the world 1-3, probably due to the recent use of colistin to combat Gram-negative carbapenem-resistant isolates 1,3,4. Here, we describe a particular case of S. marcescens infection from a single patient (P1) during four months of hospitalization. Nine S. marcescens strains, isolated from consecutive bone and soft tissue samples of P1, were subjected to antibiotype and molecular studies