INV SUPERIOR JUBILADO
PERDIGON Gabriela Del Valle
capítulos de libros
Título:
Lactic acid bacteria as immunomodulators of the gut associated immune system
Autor/es:
MALDONADO GALDEANO, CAROLINA; DE MORENO DE LEBLANC, ALEJANDRA; DOGI, CECILIA ANA; PERDIGON, GABRIELA
Libro:
Biotecnology of lactic acid bacteria: Novel applications
Editorial:
Wiley- Blackwell
Referencias:
Año: 2010; p. 125 - 140
Resumen:
Both eukaryotic and prokaryotic cells coexist in the
intestinal environment. Among the eukaryotic cells,
besides the epithelial cells, the immune cells are
organized forming the gut-associated lymphoid
tissue (GALT). The intestinal immune cells are in
contact with antigens from the external environment,
the intestinal microbiota and the antigens diet
being the main antigens stimuli. The intestinal
microbiota plays an important role in the development
of hosts innate and adaptive immune responses
and in oral tolerance mechanisms. Regulation of the
composition of the gut microbiota, for example, by
the use of prebiotics and probiotics, offers the possibility
of influencing the development of mucosal
and systemic immunity. The use of probiotics in the
prevention or treatment of intestinal infections and
the mechanisms by which these microorganisms
affect the immune system allow the determination
of the specific pathologies probiotic bacteria could
be useful to ameliorate diseases.