INVESTIGADORES
BUSTOS pamela Soledad
artículos
Título:
Flavonoids as protective agents against oxidative stress induced by gentamicin in systemic circulation. Potent protective activity and microbial synergism of Luteolin
Autor/es:
BUSTOS, PAMELA SOLEDAD; DEZA-PONZIO ROMINA; PÁEZ, PAULINA LAURA; CABRERA, JOSÉ LUIS; VIRGOLINI, MIRIAM; ORTEGA, MARÍA GABRIELA
Revista:
FOOD AND CHEMICAL TOXICOLOGY
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Lugar: Amsterdam; Año: 2018 vol. 118 p. 294 - 302
ISSN:
0278-6915
Resumen:
The flavonoids effect on gentamicin (GEN)-induced oxidative stress (OS) in systemic circulation was evaluated in terms of reactive oxygen species (ROS) production, enzymatic antioxidant defenses superoxide dismutase (SOD) and catalase (CAT), and lipid peroxidation (LP) in vitro on human leukocytes and in vivo on rat whole blood. The inhibitory activity of ROS was ATS