Direct Observation of Surface-Mediated Thioacetyl Deprotection: Covalent Tethering of a Thiol-Terminated Porphyrin to the Ag(100) Surface

OWAIN P. H. VAUGHAN; MARK TURNER; FEDERICO J. WILLIAMS; ANDREAS HILLE; JEREMY K. M. SANDERS; RICHARD M. LAMBERT

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

AMER CHEMICAL SOC

Año: 2006 vol. 128 p. 9578 - 9579

0002-7863

Covalent tethering of macromolecules such as porphyrins to metal surfaces underpins bottom-up fabrication of systems intended for a variety of applications. Thiol linkages are especially useful, but often need protection during macromolecule synthesis. By means of STM, we directly observe the spontaneous deprotection of an acetyl-protected thioporphyrin upon contact with a silver surface, without the intervention of any solution-mediated chemistry.