INVESTIGADORES
ROSENBERGER Mario Roberto
congresos y reuniones científicas
Título:
Computational modeling of a tri-leaflet mechanical heart valve
Autor/es:
MARIO ROBERTO ROSENBERGER; AMERIO, O. N.; SCHVEZOV, C. E.
Lugar:
25 al 27 de agosto de 2009, Rosario, Santa Fe, Argentina.
Reunión:
Taller; 1º Taller de Órganos Artificiales, Biomateriales e Ingeniería de Tejidos (BIOOMAT; 2009
Institución organizadora:
Asociacion Argentina de Biomateriales
Resumen:
A
tri-leaflet mechanical heart valve was designed for getting the central flow
and hemodynamic performance of a native valve. This trileaflet valve was
designed using computational fluid dynamic modeling, solving the mathematical
equations of the fluid flow assumed laminar and steady state flow. Following
the premise of design a mechanical valve with three leaves, no obstruction in
the center of the valve and peripheral pivots similar to a native valve, the
optimum design was reached by progressive changes in the form. This design was
compared with a standard bi-leaflet mechanical valve and a simplified model of
a native valve. A right artery of 24
mm in diameter and aortic sinus whit rigid wall is
assumed. For the comparison, the valves were located in this artery at 80 mm of the inlet and 200 mm of the outlet.
Prosthetic valves of 24 mm
in inner diameter were placed in suprananular position, with the leaves totally
opened. The optimum design of the tri-leaflet valve shows that the effective
surface area for flow across the valve is 84% of the total valve section; with
that design the 98% of the flow is central. On the other hand, in the
bi-leaflet valve the effective surface area is 79% of the total valve section,
and the flow is divided in three channels: two laterals (76%) and one central
(24%). For a stable flow of 5000 cm≈/min the pressure drop across the
tri-leaflet valve is of 0.07 mmHg, considerably lower than the 0.17 mmHg for
the bi-leaflet valve. As reference, the pressure drop calculated by our model
of a native valve in the same conditions is of 0.045 mmHg. The shear stress for
the tri-leaflet valve is 80% lower than for the bi-leaflet valve. It is
concluded that this tri-leaflet mechanical valve design achieves a large
central flow, which due to the large central area produce a reduced pressure
drop and a lower shear stress than for the bi-leaflet valve and consequently a
low consumption of energy and a lower risk for trombogenicity, slightly larger
to the expected in a native valve.