BIOACTIVE CHITOSAN/SILICA COATINGS BY ELECTROPHORETIC DEPOSITION TECHNIQUE FOR ENHANCING STAINLESS STEEL IMPLANTS

KATUNAR, MARIA ROSA; DIAZ, FLORENCIA; BOCCACCINI, ALDO R.; BALLARRE, JOSEFINA

Congreso; XX Congreso Internacional SAM-CONAMET 2022.; 2022

At the present time, the use of stainless steel removable screws for bone or platefixation is considered, especially in developing countries due to a costdifference with premium alloys. The improvement of implant surfaces is a keyissue to make the surgical procedure and the patient recovery, a success.Silica based bioactive glass in nanoparticles shape can be used as apatite(bone) precursors. Sol gel method, contrary to fused generated glasses, cangenerate porous and homogeneous systems, capable of enhance dissolution rates.Stoeber modified method to generate silica based nanoparticles is suitable formonodisperse nano-particle size ones. The aim of this project is to enhance thebioactivity of stainless steel implants by a chitosan electrophoretic depositedcoating containing silica-calcia nanoparticles.Cellmorphology on the different samples was also investigated by staining the cellcytoskeleton and nuclei (Figure 1). After one day of seeding, cells over 0.5nGand 0.75nG appeared to be not well spread through all surfaces but they couldrecover along the days of seeding. By day 10, increased number of cells on allsurfaces could be observed; however, in particular over 0.5nG and 0.75nGsamples cells adhesion was not homogenous. Nevertheless, cell number over0.75nG could be higher compared to 0.5nG.