INVESTIGADORES
BELIZAN Jose
artículos
Título:
Effect of the interpregnancy interval on perinatal outcomes in Latin America.
Autor/es:
CONDE-AGUDELO A, BELIZAN JM, NORTON MH, ROSAS-BERMUDEZ A.
Revista:
Obstet Gynecol
Referencias:
Año: 2005 vol. 106 p. 359 - 366
Resumen:
Objective: To estimate whether interpregnancy interval is
independently associated with increased risk of perinatal
death and other adverse perinatal outcomes.To estimate whether interpregnancy interval is
independently associated with increased risk of perinatal
death and other adverse perinatal outcomes.
Methods: We investigated the effect of interpregnancy
interval on perinatal outcomes in 1,125,430 pregnancies
recorded in the Perinatal Information System database of
the Latin American Center for Perinatology and Human
Development, Montevideo, Uruguay, between 1985 and
2004. Odds ratios (ORs) were adjusted for 16 major confounding
factors using multiple logistic regression models.We investigated the effect of interpregnancy
interval on perinatal outcomes in 1,125,430 pregnancies
recorded in the Perinatal Information System database of
the Latin American Center for Perinatology and Human
Development, Montevideo, Uruguay, between 1985 and
2004. Odds ratios (ORs) were adjusted for 16 major confounding
factors using multiple logistic regression models.
Results: Compared with infants with interpregnancy intervals
of 1823 months, those born to women with intervals
shorter than 6 months had an increased risk of early
neonatal death (adjusted OR 1.49, 95% confidence interval
[CI] 1.061.96), fetal death (adjusted OR 1.54, 95% CI
1.281.83), low birth weight (adjusted OR 1.88, 95% CI
1.781.90), very low birth weight (adjusted OR 2.01, 95%
CI 1.732.31), preterm birth (adjusted OR 1.80, 95% CI
1.711.89), very preterm birth (adjusted OR 1.95, 95% CI
1.672.26), and small for gestational age (adjusted OR
1.30, 95% CI 1.251.36). Intervals of 611 months and 60
months and longer were also associated with a significantly
greater risk for the 7 adverse perinatal outcomes.Compared with infants with interpregnancy intervals
of 1823 months, those born to women with intervals
shorter than 6 months had an increased risk of early
neonatal death (adjusted OR 1.49, 95% confidence interval
[CI] 1.061.96), fetal death (adjusted OR 1.54, 95% CI
1.281.83), low birth weight (adjusted OR 1.88, 95% CI
1.781.90), very low birth weight (adjusted OR 2.01, 95%
CI 1.732.31), preterm birth (adjusted OR 1.80, 95% CI
1.711.89), very preterm birth (adjusted OR 1.95, 95% CI
1.672.26), and small for gestational age (adjusted OR
1.30, 95% CI 1.251.36). Intervals of 611 months and 60
months and longer were also associated with a significantly
greater risk for the 7 adverse perinatal outcomes.
Conclusion: In Latin America, interpregnancy intervals
shorter than 12 months and longer than 59 months are
independently associated with increased risk of adverse
perinatal outcomes. These data suggest that spacing pregnancies
appropriately could prevent perinatal deaths and
other adverse perinatal outcomes in the developing world.
(Obstet Gynecol 2005;106:35966)In Latin America, interpregnancy intervals
shorter than 12 months and longer than 59 months are
independently associated with increased risk of adverse
perinatal outcomes. These data suggest that spacing pregnancies
appropriately could prevent perinatal deaths and
other adverse perinatal outcomes in the developing world.
(Obstet Gynecol 2005;106:35966)