BECAS
VELÁZQUEZ LÓPEZ Daniela Alejandra
artículos
Título:
Analysis of mitochondrial enzymatic activity in blood lymphomonocyte fractions during infection with different Trypanosoma cruzi strains Alejandra L. Báez1
Autor/es:
BAÉZ, ALEJANDRA; LO PRESTI, SILVINA; BAZÁN, PAOLA CAROLINA; STRAUSS, MARIANA; VELÁZQUEZ LÓPEZ, DANIELA; MILER, NOEMI; RIVAROLA, WALTER; PAGLINI, PATRICIA
Revista:
REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SãO PAULO
Editorial:
INST MEDICINA TROPICAL SAO PAULO
Referencias:
Lugar: São Paulo; Año: 2020
ISSN:
0036-4665
Resumen:
Proinflammatory and inflammatory mediators induced by Trypanosoma cruzi infection increase the oxidative stress, generating toxicity for cells targeting mitochondria of different tissues. We studied the activity of citrate synthase and complexes I-IV of respiratory chain in mitochondria of blood lymphomonocyte fraction, from albino Swiss mice infected with different isolates of T. cruzi , during Chagas disease evolution. Complexes I-IV were modified in infected groups (p