BECAS
VELÁZQUEZ LÓPEZ Daniela Alejandra
artículos
Título:
Differential tissue distribution of Trypanosoma cruzi during acute experimental infection: Further evidence using natural isolates
Autor/es:
STRAUSS, MARIANA; VEL�ZQUEZ L�PEZ, DANIELA; MOYA, DIEGO; BAZAN, CAROLINA; BÁEZ, ALEJANDRA; RIVAROLA, WALTER; PAGLINI, PATRICIA; LO PRESTI, SILVINA
Revista:
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Lugar: Amsterdam; Año: 2018
ISSN:
0166-6851
Resumen:
In the present work, we evaluated the effect of mixed Trypanosoma cruzi infections, studying the biologicaldistribution of the different parasites in blood, heart and skeletal muscle during the acute phase. Albino Swissmice were infected with different parasite strain/isolates or with a combination of them. The parasites in thedifferent tissues were typified through specific PCR, population variability was analyzed through RFLP studiesand parasitological and histopathological parameters were evaluated. We found a predominance of TcII and TcVIin all tissues samples respect to TcV and different parasite populations were found in circulation and in thetissues from the same host. These results verify the distribution of parasites in host tissues from early stages ofinfection and show biological interactions among different genotypes and populations of T. cruzi.
