White matter relapsing remitting disease: “Susac’s syndrome”—An underdiagnosed entity

SCHOTTLAENDER, LUCIA V.; CORREALE, JORGE; AMERISO, SEBASTIAN F.; MOSCHINI, JAVIER A.; CRIVELLI, LUCIA; MELI, FRANCISCO; FIOL, MARCELA P.

Multiple Sclerosis and Related Disorders

Elsevier Inc

Lugar: Amsterdam ; Año: 2013 vol. 2 p. 349 - 354

2211-0348

The objective of this study is to assess attention in recently diagnosed relapsing-remitting multiple sclerosis patients.Twenty-seven patients with early multiple sclerosis and low clinical disability scores (EDSS,2) and 27 sex-, age-, andeducation-matched healthy controls underwent attention assessment using the Attentional Network Test, a computerizedtask designed to measure efficiency independently in 3 attentional networks (Alerting, Orienting and Executive Control).MS patients had significantly less efficiency in the Alerting network (p 5 .006). In contrast, in the Orienting and ExecutiveControl networks, they did not differ from controls. A significant interaction between Alerting and Executive Control wasalso found in the MS patients (p 5 .007). Early relapsing-remitting multiple sclerosis particularly affects the Alerting domainof attention, whereas the Orienting and Executive Control domains are not affected. (JINS, 2012, 18, 757?763)