The effect of mono- or biparental care on alcohol-induced motor stimulation and neural activation in infant mice.

PASQUETTA, L.; WILLE-BILLE, A.; FERREYRA, E.; RAMIREZ, A.; MIRANDA MORALES, RS

Congreso; LASBRA; 2019

Parental behavior during early development has a strong influence on the emotional and social development of infants. Literature on parenting, human or animal, has primarily focused on the interactions between mothers and offspring, with little research directed at understanding on whatpaternal behavior could add to infant social attachment. Previous studies have shown that strongsocial attachment as pair bond formation in adult rodents has protective effects against drugeffects. In this sense, parenting conditions during infant development may have differential effectson drug experience. We have evidenced that monoparental (ie., single mother) rearing condition in c57bl/6 mice induced an anxiety-like behavior and major alcohol consumption in adolescent offspring. Here, we aimed to analyze if mono- or biparental conditions could alter alcohol-induced locomotor stimulation and its effects on neural activation in several brain areas.