INVESTIGADORES
MENDICINO Diego Antonio
artículos
Título:
Simultaneous use of two Rapid Diagnostic Test for the diagnosis of Chagas´Disease
Autor/es:
MENDICINO DIEGO; COLUSSI CARLINA; MORETTI EDGARDO
Revista:
TROPICAL DOCTOR
Editorial:
ROYAL SOC MEDICINE PRESS LTD
Referencias:
Lugar: LONDRES; Año: 2019 vol. 49 p. 23 - 26
ISSN:
0049-4755
Resumen:
Sensitivity of rapid diagnostic tests (RDT) for Chagas´ disease is not high enough fortheir use as unique method. The aim of this work was to evaluate the performance oftwo RDT for Chagas´ disease used simultaneously. Two different RDT (A and B) wereperformed in 64 and 42 serum samples that were negative and positive, respectively,by conventional serological techniques. Validity and reliability of both tests wereevaluated individually and simultaneously. Sensitivity was 90.5% and 97.6%, andspecificity was 100% and 93.8%, for RDT A and B, respectively. The Kappa statistic was0.96. When both RDTs were used simultaneously, sensitivity was 97.4%, specificity was100% and the percentage of discordant 6.6%. The combined use of two RDT withserum samples is a suitable alternative for application in health care centers.
