Physical Activity, Sedentary Time and Cardiorespiratory Fitness Associations with Short- Term Heart Rate Variability and Inflammatory and Oxidative Stress Markers

DEL ROSSO SEBASTIAN; BARAQUET MARÍA LUCIA; MAZZOCO YANINA LUCIANA; BERGERO GASTÓN; AOKI MARIA PILAR; PEROVIC NILDA RAQUEL

Congreso; European College of Sport Science; 2021

INTRODUCTION:The objective was to assess the associations between objectively measured physical activity (PA), sedentary behavior (SB), and cardiorespiratory fitness (CRF) with indices of heart rate variability (HRV), and plasma inflammatory and oxidative stress markersMETHODS: 44 participants [29 women, 15 men, age=49.5(6.4) yrs, BMI=28.1 (6.2) kg·m-2] from the ?Lifestyles and Oxidative Stress Markers in Cardiometabolic Risk Study?. Data were collected between 7.00-10.00 A.M. in a fasted state and without prior consumption of coffee, tea, or tobacco; in the following order: Resting heart (HR) rate for HRV analysis (SDNN, RMSSD, LF, HF, LF/HF, SD1, SD2, Sample Entropy, PNS and SNS index), a blood sample to measure inflammatory [C-reactive protein (CRP) and cytokines (IL-1ß, INF-G, TNF, MCP-1, IL-6, IL-8, IL-10, IL-18, IL-23] and oxidative stress markers [Catalase (CAT) and Glutathione Peroxidase (GPX)], anthropometric measures, a submaximal cycling test for VO2max estimation with active recovery to assess absolute HR recovery (30s, 1, 2, 3, 4, 5 min), Deltas (30, 1, 2, 3, 4, 5) and HRR kinetics [time constant (t), and amplitude (HRRamp)] and 7-day PA monitoring [time sedentary, time in light PA (LPA) and time in moderate to vigorous PA (MVPA)]. Non-normal distributed variables log-transformed (ln) and all statistics were performed at a=0.05RESULTS:Women spent more time in SB (P=0.035, ES=0.72) whit less sedentary breaks (P=0.014, ES=0.43), higher ln IL-6 (P=0.02, ES=0.84) and ln TNF (P=0.01, ES=0.97) and lower HRV indices [SDNN, LF/HF, SD2 (P>0.05)] than men. There were no significant differences in PA or SB between groups defined by a determined CRF. However, the group with high CRF showed lower values of ln TNF (P=0.02) and IL-10 (P=0.003), a tendency for lower ln IL-1ß and ln IL-6 (P=0.05) and higher HRV indices [RMSSD, PNS, SampEn, SD1 (P