Self-assembled vesicles obtained by electrohydrodynamic technique using different sources of phospholipids

SANCHEZ CERVIÑO, MARIA CELINA; DI GIANVINCENZO, P; MOYA, S; RIVERO, GUADALUPE

Mar del Plata

Congreso; XII Latin-American Congress of Artificial Organs and Biomaterials; 2023

INTEMA (UNMdP-CONICET) y LABOATEM (UNR-CONICET)

Vesicles are supramolecular structures composed of one or multiple bilayers of amphiphilic molecules that surround an aqueous compartment. Due to the characteristics and versatility of the structures, they can hold both hydrophobic and/or hydrophilic therapeutic agents. However, their production requires many steps, and they are unstable in storage. In this work, vesicles were obtained from a non-traditional method, using solid electrospun membranes as templates that form vesicles by self-assembly when dissolved in water.The objective is to test different compositional parameters, raw materials´ qualities and their storage stability.