Is tremor related to Celiac disease?

LUCIA AMEGHINO; MALCO ROSSI; DANIEL CERQUETTI; MARCELO MERELLO

Berlin

Congreso; 20th International Congress of Parkinson?s Disease and Movement Disorders; 2016

BACKGROUND: Celiac disease (CD) is a systemic autoimmune disease, whose prevalence is of about 1% worldwide. Neurological manifestations include ataxia, myoclonus, polyneuropathy, epilepsy and headache, with an overall prevalence of 5-36%. Tremor has been scarcely described.OBJECTIVES: To evaluate the prevalence and clinical correlates of tremor in CD. MATERIAL AND METHODS: An online inquest using an essential tremor screening scale (WHIGET) and validated to Spanish was published in the Argentinean Celiac Association website from June through July 2015. Demographic data, celiac antibodies and diet compliance were recorded. The same survey was also applied to an age and gender-matched control group comprised by non- blood relatives. Only CD patients with bowel biopsy confirmation (Marsh score ≥ III) were included. Data were analyzed using chi square test and ANOVA test.RESULTS: Fifteen hundred and twelve subjects completed the survey, of which 964 (64%) were included: 674 (69.9%) had CD and 290 (30.1%) were controls. Female gender was more frequent in CD group than in controls (92% vs 81%, p