CLINICAL FEATURES IN PATIENTS WITH CANCER AND COVID-19 IN SANTA FE AND BUENOS AIRES

GASTIAZORO MP; CARDOZO MA; RAMOS JG; BALLINA A; MAILLO M; BERNAL MF; BERGERO M; CALAFELL G; CAYOL F; BOSSIO JC; VARAYOUD J

Congreso; Reunión conjunta SAIC - SAi - AAFE; 2021

Patients with cancer are high-risk population in the COVID-19 pandemic. We aimed to describe clinical characteristics of patients with cancer and COVID-19 in city of Santa Fe and Buenos Aires. We did a cross-sectional study of 80 patients with laboratory-confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and with a pathological diagnosis of a malignant tumor from hospitals of city of Santa Fe and from Hospital Italiano (Buenos Aires). Clinical characteristics and cancer histories were investigated and analyzed. During the study, 80 patients with cancer and laboratory-confirmed SARS-CoV-2 infection were included (median age 65 years). 45 (56,2%) patients were women and 34 (42,5%) were men. 72 patients had solid tumours and 3 patients had haematological malignancies. The most frequently symptoms were fever (29 [40,28%] patients) and cough (28 [38,89%] patients); then dyspnoea (18 [25%] patients) and fatigue (19 [26,36%] patients). The most common solid tumor types were breast (20 [26,7%] patients) and lung cancer (8 [10,7%] patients). 33 (41,25%) of 80 patients had comorbidities: 11 (20,37%) had coronary disease, 10 (18,52%) had diabetes, 7 (12,96%) had chronic kidney disease and 5 (9,26%) chronic obstructive pulmonary disease. The rate of mortality was of 18.75%. In addition, if we analyze how many patients did not survive among the cases with severe pneumonia (41,86%) and compare them with non-severe pneumonia (16,28%), it gives an OR of 20.25 (2.32, 176.6, p = 0.0028), indicating that severe pneumonia could be a risk factor of mortality. Current statistics data from Argentina indicate that the rate of mortality of COVID-19 patients was 2% (114000 of 5240000). The data from our analysis indicates that cancer and COVID-19 patients have an 8 times higher risk of death than patients with only COVID-19.