Natural Antifungal Agents Isolated from Argentine Plants. A Summary of Studies Developed in the Period 2000?2020

GISELA SEIMANDI; ESTEFANÍA BUTASSI; MELINA DI LIBERTO; CORDISCO ESTEFANÍA; ALAN BLANC; MAXIMILIANO SORTINO; LAURA SVETAZ; MARCOS DERITA

Promising Antimicrobials from Natural Products

Springer

Año: 2022; p. 281 - 313

Basidiomycota mushrooms are one of the best and rich sources of natural bioactive compounds, including antitumor, antioxidant, antimicrobial, and many others. The search for natural sources of chemically new, safe, and effective antibiotics for biological control of invasive organisms and the development of effective and competitive technologies for their productionhas become a scientiic and technological challenge. This chapter mostly summarizes recently published reports and own data on the occurrence of antibacterial and antifungalactivities among Basidiomycota species collected from different geographical regionsand ecological niches. Antibiotic activities of extracts from fruiting bodies and mycelial cultures against different groups of microorganisms are compared, focusing on the diversity, common characteristics, and unique properties of individual mushrooms, as well as on several physiological approaches and strategies that enhance the biosynthetic potential of mushrooms and their antimicrobial activity to provide a sustainable source of a safe, useful, and cheap medicine for the treatment of infectious diseases.