Nanophase ceramic particles in bone regenerative therapeutics: theranostic platforms for bone disorders

MESSINA, PAULA V.; PISTONESI, DENISE B.; BELÉN, FEDERICO

Inorganic Nanosystems, Theranostic Nanosystems

El Seiver, Academic Press

Año: 2023; p. 28 - 646

The chapter "Nanophase ceramic particles in bone regenerative therapeutics: theranostic platforms for bone disorders" focuses on the application of nanophase ceramic particles in bone regenerative therapies.Firstly, the characteristics of ceramic materials and their use in bone tissue engineering are described. The chapter explains how the structure and composition of these materials can influence bone regeneration, and how nanophase particles can further enhance their performance in bone regeneration.The chapter also covers the use of nanomaterials in the diagnosis and treatment of bone diseases, including osteoporosis and bone cancer. It explains how nanophase ceramic particles can be used for controlled drug and gene therapy delivery, allowing for greater effectiveness in treating these diseases.In addition, the use of advanced medical imaging such as positron emission tomography (PET) and single photon emission computed tomography (SPECT) in combination with bone regenerative therapies is discussed. These imaging techniques allow for accurate evaluation of bone regeneration progress and therapy effectiveness.The chapter also addresses the challenges in using nanophase ceramic particles in bone regenerative therapies, including the need for a thorough understanding of the interactions between particles and tissues, and the need to develop high-quality manufacturing techniques to ensure particle uniformity.In summary, the chapter "Nanophase ceramic particles in bone regenerative therapeutics: theranostic platforms for bone disorders" provides a detailed overview of how nanophase ceramic particles can be used in bone regeneration, diagnosis, and treatment of bone diseases, highlighting the opportunities and challenges in this field.