INVESTIGADORES
FRECHTEL Gustavo Daniel
artículos
Título:
The rs1801278 G>A polymorphism of IRS-1 is associated with metabolic syndrome in healthy nondiabetic men. Modulation by cigarette smoking status.
Autor/es:
PÉREZ MS, TELLECHEA ML, ARANGUREN F, TAVERNA MJ, RODRÍGUEZ RG, MEROÑO T, BRITES F, POSKUS E, FRECHTEL GD
Revista:
DIABETES RESEARCH AND CLINICAL PRACTICE
Editorial:
ELSEVIER IRELAND LTD
Referencias:
Año: 2011
ISSN:
0168-8227
Resumen:
AIMS:
To explore associations between IRS-1 rs1801278 G>A polymorphism and metabolic syndrome (MS).
METHODS:
rs1801278 G>A was genotyped in 610 healthy Argentinian men.
RESULTS:
GA carriers had lower risk of MS (OR=0.52, P=0.045), particularly among smokers (OR=0.10, P=0.006).
CONCLUSIONS:
rs1801278 GA carriers had lower risk of MS, especially among smokers.
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.
