INVESTIGADORES
SESMA Juliana Ines
artículos
Título:
Signaling and Pharmacological Properties of the P2Y14 Receptor
Autor/es:
T. K. HARDEN; J. I. SESMA; I. P. FRICKS; E. R. LAZAROWSKI
Revista:
ACTA PHYSIOLOGICA
Editorial:
WILEY-BLACKWELL PUBLISHING, INC
Referencias:
Lugar: Londres; Año: 2010 vol. 199 p. 149 - 160
ISSN:
1748-1708
Resumen:
The P2Y14 receptor is a relatively broadly expressed G protein-coupled receptor that is prominently associated with immune and inflammatory cells as well as with many epithelia. This receptor historically was thought to be activated selectively by UDP-glucose and other UDP- sugars. However, UDP is also a very potent agonist of this receptor, and may prove to be one of its most important cognate activators.