PERSONAL DE APOYO
TAU Julia
artículos
Título:
Tear Lysozyme in Sjögren´s syndrome, Meibomian gland dysfunction, and non-dry-eye Lisozima lacrimal na síndrome de Sjögren, disfunção da glândula meibomiana e olho não seco
Autor/es:
BERRA, MARTÍN; GALPERÍN, GUSTAVO; BERRA, FEDERICO; MARQUEZ, MARIA ISABEL; MANDARADONI, MARIANA; TAU, JULIA; BERRA, ALEJANDRO
Revista:
ARQUIVOS BRASILEIROS DE OFTALMOLOGIA
Editorial:
CONSEL BRASIL OFTALMOLOGIA
Referencias:
Año: 2021 vol. 85 p. 103 - 108
ISSN:
0004-2749
Resumen:
Purpose: To evaluate the concentration of tear lysozyme in individuals with Sjogren´s syndrome, meibomian gland dysfunction, and non-dry-eye disease. Methods: Ninety subjects were recruited for this study, including 30 with Sjogren´s syndrome, 30 with meibomian gland dysfunction, and 30 with non-dry-eye disease. All subjects were referred to participate in the study based on a dry eye investigation. They underwent a complete ocular surface ophthalmic examination encompassing ocular surface disease index, biomicroscopy, tear break-up time, Schirmer test type I, conjunctival vital staining with fluo-rescein and lissamine green, tear lysozyme concentration, and impression cytology. Results: Clinical tests yielded the following results: ocular surface disease index Sjogren´s syndrome: 64.5 ± 22.6 meibomian gland dysfunction: 43.5 ± 21.4, non-dry-eye disease: 6.7 ± 4.3 (p=0.02 between groups); Schirmer I test (mm/5 min): Sjogren´s syndrome: 4.95 ± 2.25, meibomian gland dysfunction: 13.28 ± 1.53, non-dry-eye disease 13.70 ± 1.39 (p
