BECAS
PAYASLIAN Florencia PÍa
congresos y reuniones científicas
Título:
HLA-Class II expression identifies functionally distinct human CD8+ regulatory T cells
Autor/es:
LOURDES ARRUVITO; FLORENCIA PAYASLIAN; ARIEL PODHORZER; JULIETA PANDOLFI; LEONARDO FAINBOIM
Lugar:
Los Cocos, Cordoba
Reunión:
Congreso; LXI Reunión Anual de la Sociedad Argentina de Inmunología; 2013
Institución organizadora:
Sociedad Argentina de Inmunologia
Resumen:
Human suppressor T cells were defined within the CD8+ T-cell compartment in early 80 by us. However, since the characterization of the CD4+FOXP3+ Tregs, CD8+ Tregs fall into an ill defined subset of regulatory T cells. In the present study we re-evaluated our first description of a subset of induced CD8+HLA-DR+ cells with a strong suppressor activity. The main aim was to identify this subset in resting CD8+ T cells from peripheral blood as a counterpart of natural CD4+FOXP3+ Tregs.
