Characterizing the biomechanics of an endovascular intervention in cerebral aneurysms using Kirchhoff-Love shells of nonuniform thickness

MUZI, NICOLÁS; FRANCESCO CAMUSSONI; MOYANO, LUIS G.; DANIEL MILLÁN

Strasbourg

Conferencia; XVI Computational Biomechanics for Medicine; 2021

University of Western Australia

Rupture of intracranial aneurysms is the most common cause of spontaneoussubarachnoid bleeding, related to high morbidity and mortality rates. However,intracranial aneurysms have a higher prevalence than that due to their spontaneousrupture rate, exacerbated by the risks associated with occlusion intervention, whichmotivates the development of technological tools to support clinical diagnosis andendovascular occlusion intervention planning. In particular, the aneurysm dome issensitive to applied loads in the contiguous surroundings to the aneurysm neck. Indeed,this region shows high complexity due to the arterial wall nature of the pathology. Thiswork presents preliminary statistical analysis results of a thin shell model, with varyingmaterial and geometrical parameters, under a localized load emulating the effect of amicrocatheter pressing the neck area. In a selection of 34 cases, we show thatdimensionality reduction techniques such as Isomap can help determine non-trivialregions of interest under concentrated loads, leading to more general machine learningclassification models for sensitive area identification.