Transcriptional analyses of the region of the EHV-4 genome encoding glycoproteins I and E

DAMIANI A., JANG H-K., MATSUMURA T., MIYAZAWA, T., MIKAMI T

ARCHIVES OF VIROLOGY

SPRINGER WIEN

Lugar: Viena; Año: 1999 p. 613 - 620

0304-8608

To map the transcripts encoding the equine herpesvirus type 4 (EHV-4) glycoproteins I (gI) and E (gE), transcriptional analyses were performed at the right part of the unique short segment of EHV-4 genome. The results revealed that the gI gene is encoded by a 1.6-kb transcript which is 30 coterminal with a 3.0-kb gD mRNA while the gE gene is encoded by two transcripts of 3.5- and 2.4-kb in size. The transcriptional patterns described in this study for the EHV-4 gI and gE are similar to those found in the equivalent region of herpes simplex virus type 1 and feline herpesvirus type 1. Characterization of EHV-4 gI and gE glycoprotein genes may facilitate future studies to define their roles in the EHV-4 infection.