1,3-Dipolar Cycloaddition in N-O Heterocycles Synthesis. Advances and Applications

MIRTA L. FASCIO; NORMA B. D´ACCORSO

Modern Approaches to the synthesis of O- and N-Heterocycles. Vol 2.

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Lugar: Kerala - India.; Año: 2007; p. 79 - 108

1,3-Dipolar cycloadditions are one of the most powerful methods for the construction of a variety of five-membered heterocycles. Particularly, nitrile oxide chemistry has been widely used to obtain isoxazoline and isoxazole rings. These heterocycles are key intermediates for the synthesis of a great number of natural products; in addition, these systems show interesting biological applications