INVESTIGADORES
PESCE VIGLIETTI AyelÉn Ivana
congresos y reuniones científicas
Título:
B cells in ostearticular disease caused by Brucella abortus.
Autor/es:
AYELÉN IVANA PESCE VIGLIETTI; PAULA CONSTANZA ARRIOLA BENITEZ; GUILLERMO HERNÁN GIAMBARTOLOMEI; MARÍA VICTORIA DELPINO
Lugar:
Buenos Aires
Reunión:
Congreso; I meeating LACID - FAIC - SAI; 2015
Institución organizadora:
LACID - FAIC - SAI
Resumen:
Osteoarticular brucellosis is the most common localization of human active disease. B cells play an important rol in osteoarticular disease since they can produce factors that induce osteoclast differentiation (cells involved in bone resorption). The aim of this study was to determine if Brucella abortus (Ba) infection could activate B cells. B cells were purified by negative selection using magnetic beads, and de purity was corroborated using anti-CD19-FITC and anti-B220-PE antibodies. Ba infection induces the surface expression of RANKL (p
