Effect of Cynara scolymus and Silybum marianum extracts on bile production in pigs

GUADALUPE MARTINEZ; SUSANA NELLY DIEGUEZ; EDGARDO RODRIGUEZ; JULIETA MARÍA DECUNDO; AGUSTINA ROMANELI; MARÍA BELÉN FERNÁNDEZ PAGGI; DENISA SOLEDAD PEREZ GAUDIO; FABIAN ANDRÉS AMANTO; ALEJANDRO LUIS SORACI

JOURNAL OF APPLIED ANIMAL RESEARCH

GARUDA SCIENTIFIC PUBLICATIONS

Año: 2018 vol. 46 p. 1059 - 1063

0971-2119

Many of the beneficial effects on productive performance observed when vegetable extracts areincorporated as feed additives in intensive farming can be explained by an increase in bile production.An experiment was conducted to study choleretic and cholagogue effect of a Cynara scolymus extractformulation and of silymarin in pigs. Pigs were cannulated with a T-tube catheter in the bile duct. Bileproduction was continuously measured and re-infused to the duodenum through Oddi?s sphincter atthe same production rate. Treatments: Group A (n = 6), commercial feed; Group B (n = 6), C. scolymusextract (300 g/tonne) and Group C (n = 6), silymarin (300 g/tonne). Bile production was recorded hourlyfor each animal during 24 h. Total bile acids? concentrations in bile, just before and one hour aftermeals were evaluated. Average daily bile production for pigs in group B was 66% higher than for pigsin groups A or C (P < .05). When bile acids? concentrations before and after meals were compared, onlypigs from group B exhibited an increase (P = .0023). From this study, it was concluded that neithercholeretic nor cholagogue effects are attained with silymarin supplementation. On the contrary, C.scolymus extract increases bile production and secretion in pigs.