INVESTIGADORES
VIGLIANO Carlos
artículos
Título:
Seronegative conversion after incomplete benznidazole treatment in chronic Chagas disease.
Autor/es:
ALVAREZ MG; VIGLIANO CA; LOCOCO B; PETTI M; BERTOCCHI G; VIOTTI R
Revista:
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE
Editorial:
ELSEVIER SCIENCE INC
Referencias:
Año: 2012 vol. 106 p. 636 - 638
ISSN:
0035-9203
Resumen:
In 12-18% of adult patients, treatment with benznidazole for chronic Chagas disease has to be discontinued because of side-effects. We identified and analysed a cohort of 81 adult patients with three positive tests for Trypanosoma cruzi infection and serological monitoring following incomplete treatment with benznidazole for a median of 10 days. Twenty percent of these patients (16/81) met the criteria of cure, showing that the optimal schedule of benznidazole administration remains to be determined.