Evaluation of the Diagnostic Performance of the Ocular Response Analyzer for Subclinical Keratoconus

FUENTES BONTHOUX FERNANDO; GALLETTI JEREMÍAS GASTÓN; PFÖRTNER TOMÁS

Fort Lauderdale, FL

Congreso; ARVO 2011 Annual Meeting; 2011

ARVO

Purpose:To evaluate the performance of previously derived diagnostic cutoff points for corneal hysteresis (CH) and corneal resistance factor (CRF) for detecting subclinical keratoconus. Methods:65 eyes from 65 healthy subjects in group 1 and 67 eyes from 67 keratoconus patients were evaluated with Ocular Response Analyzer (ORA), corneal topography, aberrometry and anterior segment optical coherence tomography. Only eyes with central corneal thickness (CCT) between 441 and 560 µm were included, and for group 2, the eye with the lowest average corneal power (ACP) was chosen. Observations were stratified in 20-µm intervals to which cutoff points obtained from previous work on an independent sample were applied. The Keratoconus Severity Score (KSS) was used to grade keratoconus. Results:Group 2 eyes had lower CCT (µm, 515.1±3.516 vs 492.0±3.386, p