INVESTIGADORES
SANZ BLASCO Sara Isabel
artículos
Título:
Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells
Autor/es:
ZHU S; AMBASUDHAN R; SUN W; KIM HJ; TALANTOVA M; WANG X; ZHANG M; ZHANG Y; LAURENT T; PARKER J; KIM HS; ZAREMBA JD; SALEEM S; SANZ BLASCO S; MASLIAH E; MCKERCHER SR; CHO YS; LIPTON SA; KIM J; DING S
Revista:
CELL RESEARCH
Editorial:
INST BIOCHEMISTRY & CELL BIOLOGY
Referencias:
Lugar: Shanghai; Año: 2013 p. 1 - 4
ISSN:
1001-0602
Resumen:
We previously developed a novel paradigm of cell activation and signaling-directed (CASD) lineage conversion for direct reprogramming of fibroblasts into cardiac, neural and endothelial precursor cells. This method is based on the transient overexpression of iPSC factors (cell activation, CA) in conjunction with lineage-specific soluble signals (signaling directed, SD).
