Adiponectin and waist circumference as predictors of insulin-resistance in women

BONNEAU GA; PEDROZO WR; BERG G

Diabetes & Metabolic Syndrome: Clinical Research & Reviews

elsevier

Año: 2014 vol. 8 p. 3 - 7

1871-4021

BACKGROUND AND AIMS: The initial disturbance of insulin resistance seems to focus on adipose tissue is a dynamic organ involved in many physiological and metabolic processes. Expresses and secretes a variety of active peptides, adipocytokines. To evaluate the prevalence of insulin-resistance in an healthy urban middle age population and to explore the role of adiponectin, inflammatory biomarkers (hs-CRP) and traditional cardiovascular risk factors as predictors of the insulin-resistance state. MATERIALS AND METHODS: We studied of 176 participants (117 women and 59 men, 25-74 years), individuals with diabetes, hypothyroidism or hyperthyroidism, infectious disease, renal, or hepatic neoplasms and pregnant women were excluded. We evaluated glucose, insulin, adiponectin and hs-CRP. RESULTS: We found that 17.2% of individuals presented insulin-resistance. Correlation was found between waist circumference, body mass index, blood pressure and HOMA index (p