Validation of the Spanish Version of the Addenbrooke's Cognitive Examination-Revised (ACE-R).

TERESA TORRALVA; MARIA ROCA; EZEQUIEL GLEICHGERRCHT; A, BONIFACIO; CATALINA RAIMONDI; FACUNDO MANES

NEUROLOGIA

Sociedad Española de Neurología

Año: 2011 vol. 26 p. 351 - 356

BACKGROUND: The Addenbrooke´s Cognitive Examination Revised (ACE-R) is an improved version of the earlier brief screening test which has been validated in English with high sensitivity and specificity to detect cognitive dysfunction. The aim of this study was to validate the Spanish version of the ACE-R in an Argentine population. METHODS: A group of patients with Alzheimer Disease (AD) and patients with behavioural variant Frontotemporal Dementia (bvFTD) paired by age, sex, and years of education with healthy controls were assessed using the ACE-R. Stage of dementia was measured with the Clinical Dementia Rating Scale (CDR). The English version of the ACE-R was first translated into Spanish and then back-translated into English by two blind independent experts. RESULTS: Internal reliability was very good (Cronbach´s alpha=0.89). Concurrent validity, determined by the correlation between total ACE-R and CDR was significant (P