Decision making cognition in primary progressive aphasia.

EZEQUIEL GLEICHGERRCHT; TERESA TORRALVA; MARIA ROCA; DANIELA SZENKMAN ; AGUSTIN IBANEZ; PABLO RICHLY; MARIA ANGELES POSE; FACUNDO MANES

BEHAVIOURAL NEUROLOGY

IOS PRESS

Lugar: Amsterdam; Año: 2012 vol. 25 p. 45 - 52

0953-4180

We sought to investigate the decision making profile of Primary Progressive Aphasia (PPA) by assessing patients diagnosed with this disease (n = 10), patients diagnosed with behavioral variant frontotemporal dementia (bvFTD, n = 35), and matched controls (n = 14) using the Iowa Gambling Task, a widely used test that mimics real-life decision making. Participants were also evaluated with a complete neuropsychological battery. Patients with PPA were unable to adopt an advantageous strategy on the IGT, which resulted in a flat performance, different to that exhibited by both controls (who showed advantageous decision making) and bvFTD patients (who showed risk-appetitive behavior). The decision making profile of PPA patients was not associated with performance on language tasks and did not differ between sub-variants of the disease (namely, semantic dementia and progressive nonfluent aphasia). Investigating decision making in PPA is crucial both from a theoretical perspective, as it can shed light about the way in which language interacts with other cognitive functions, as well as a clinical standpoint, as it could lead to a more objective detection of impairments of decision making deficits in this condition.