In Vitro Susceptibility to Metronidazole of Tritrichomonas foetus Bovine Isolates from Argentina

RIVERO, MARÍA BELÉN; LUQUE, MELCHOR EMILIO; ABDALA, MARIA EUGENIA; LUNA, BRUNO ELÍAS; DI LULLO, DAVID; ECHAIDE, IGNACIO EDUARDO; CARRANZA, PEDRO GABRIEL; RIVERO, FERNANDO DAVID

ACTA PARASITOLOGICA

VERSITA

Lugar: Varsovia; Año: 2019

1230-2821

AbstractBackground Tritrichomonas foetus is the etiologic agent of the sexually transmitted disease Bovine Trichomonosis (BT).In Argentina, BT is endemic and represents a relevant health problem that causes reproductive inefficiency in cattle andlarge economic losses. Metronidazole is the drug of choice in the treatment of BT. Treatment has been associated with atemporary resolution of the clinical signs but is not able to control the disease. In recent years, the apparition of in vivo andin vitro aerobic and anaerobic resistance leading to ineffective treatments has been reported.Aims Thus, the aim of the present study was to explore the susceptibility of six different isolates of T. foetus under aerobic(AC) and anaerobic (ANC) conditions.Results and discussion Six isolates of T. foetus were obtained from samples of preputial smegma of bovine origin. Values ofminimum lethal concentration and minimum inhibitory concentration were higher than those observed in other works andrepresent current data in Argentina and provide information to establish new treatment protocols.