Asociación entre educación materna y presión arterial en adultos: Evidencia de mediación a través de la estatura y sus componentes en ELSA-Brasil

RODRÍGUEZ LÓPEZ, SANTIAGO; ISABELA BENSEÑOR; LUANA GIATTI; MOLINA, MCB; PAULO A. LOTUFO

La Habana

Congreso; CONVENCIÓN INTERNACIONAL DE ANTROPOLOGÍA ANTHROPOS 2015 XII SIMPOSIO DE ANTROPOLOGÍA FÍSICA LUIS MONTANÉ.; 2015

Introduction: Better childhood conditions -mainly inferred from height and leg length- are usually protective against CHD in high-income countries. However, evidence is mixed about the nature of these associations in low- and middle-income countries or in locations where economic development is more recent. Objective: Evaluate the association between components of health and blood pressure in Brazilian adults.Methods: Linear regression was used to assess the associations between components of height (total height, trunk and leg lengths, and leg-to-trunk ratio) and systolic (SBP) and diastolic blood pressures (DBP), in a cross-sectional sample of 13,571 Brazilians aged 34-75 from the ELSA-Brasil study.Results: Higher stature and longer legs were associated with lower SBP and DPB in the age-adjusted analysis. The components of height-SBP associations were robust after adjustments for early life conditions such as ethnicity and maternal education, and other confounder in full adjustment. After adjusting for leg length when trunk length was the exposure of interest -and vice versa, the associations between trunk and leg lengths with SBP were somehow attenuated ?although remained statistically significant- for men. Among women, the association between trunk length and SBP was attenuated to non-significant values, while the estimate for leg length was unchanged (-0.925 (-1.291; -0.559)). Conclusions: The protective effect of the components of height on adult BP reported in high-income countries is also present in a middle-income country like Brazil. In order to prevent CHD in old-age, efficient interventions could be intended to improve early stages of people?s life.