INVESTIGADORES
TRUCCO BOGGIONE Carolina
artículos
Título:
Weak D antigen expression caused by a novel RHD allele in Argentineans
Autor/es:
TRUCCO BOGGIONE, CAROLINA; LUJÁN BRAJOVICH, MELINA ELIANA; GASPARDI, ANE CAROLINE; SIPPERT, EMILIA; MATTALONI, STELLA MARIS; LERI, MÓNICA; BIONDI, CLAUDIA; CASTILHO, LILIAN; COTORRUELO, CARLOS
Revista:
TRANSFUSION
Editorial:
WILEY-BLACKWELL PUBLISHING, INC
Referencias:
Lugar: Londres; Año: 2016
ISSN:
0041-1132
Resumen:
RHD polymorphism shows substantial ethnic variability. In this study, we report the novel RHD exon 3 c.359C>A mutation responsible for the amino acid change p.Ala120Asp found in 28 individuals from Argentina with weak D antigen expression. The RHD*359A allele was only encountered in samples with ccEe phenotype suggesting a genetic cis association between this new RHD variant and the RHcE allele.
