INVESTIGADORES
MENACHO MÁRQUEZ Mauricio Ariel
artículos
Título:
Genotoxic activity of halogenated phenylglycine derivatives
Autor/es:
BOTO, A; GALLARDO, A; HERNÁNDEZ, R; LEDO, F; MUÑOZ, A; JOSÉ RAMÓN MURGUÍA; MAURICIO ARIEL MENACHO; ORJALES, A; SAAVEDRA, C
Revista:
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Lugar: Amsterdam; Año: 2006 vol. 16 p. 6073 - 6077
ISSN:
0960-894X
Resumen:
The discovery of genotoxic amino acids derived from phenylglycine, and posessing halogen substituents, is described. The utility of hypervalent iodine reagents in the synthesis of this class of compounds is highlighted. The mechanism of action of the (haloaryl)glycines was studied in Saccharomyces cerevisiae.
