Central vs. peripheral circadian control of oviposition in Drosophila melanogaster.

PAULA DRAUSAL; GUADALUPE CASCALLARES; SEBASTIAN RISAU GUSMAN; PABLO GLEISER; M.FERNANDA CERIANI; D. LORENA FRANCO

Montevideo

Congreso; International Congress of Neuroethology 2016; 2016

International Society for Neuroscience

The circadian system allows time synchronizationof vital biochemical,cellular and physiological processes withcyclical environmental events in a wide array of organisms. TheDrosophila circadian clock is controlledby interlocked transcriptional feedback loops present in neuronal andnon-neuronal tissues. The periodic egg-laying behavior, or oviposition, in Drosophila is one of the severalphysiological processes regulated in a circadian fashion. However, thisrhythmic behavior is poorly studied and manyimportant aspects related with the role of the molecular clock remains to be elucidated. Todemonstrated that the circadian control of oviposition is regulated by themolecular clock, we used null mutants for perand tim, the genes responsible forthe molecular clock function. Moreover, to study if this circadian behaviour is centrally or peripheral regulated, wedownregulated the expression of per exclusivelyin the brain. Preliminary results indicate that the brain molecular clock isnecessary for the rhythmic oviposition behavior, since a reduction of per levels only in the brain inducesarrythmicity.