Viral Studies Point the Way: Mechanisms of Intercellular Transport

PEÑA, EDUARDO; NIEHL, ANNETTE; HEINLEIN, MANFRED

Short and Long Distance Signaling

Springer

Lugar: new york; Año: 2012; p. 1 - 43

Plant development depends on the intercellular transport of macromolecules through gatable channels in the cell wall known as plasmodesmata (PD). Plant viruses exploit this intercellular trafficking pathway to move cell-to-cell and to cause systemic infection. Dependent on viral species, movement through PD can occur in virion or non-virion form and by different mechanisms for targeting and modification of the pore. These mechanisms are supported by viral movement proteins and by other virus-encoded factors that interact among themselves and with plant cellular components to facilitate virus movement in a coordinated and regulated fashion. This chapter provides an overview about current knowledge in virus cell-to-cell movement with the aim to extract principal mechanisms playing a role in intercellular transport.