INVESTIGADORES
PEÑA Eduardo Jose
artículos
Título:
Cortical microtubule-associated ER sites: organization centers of cell polarity and communication
Autor/es:
EDUARDO JOSÉ PEÑA; HEINLEIN, MANFRED
Revista:
CURRENT OPINION IN PLANT BIOLOGY
Editorial:
CURRENT BIOLOGY LTD
Referencias:
Lugar: Londres; Año: 2013 vol. 16 p. 764 - 773
ISSN:
1369-5266
Resumen:
Anisotropic cell
growth and the ability of plant cells to communicate within and across
the borders of cellular and supracellular domains depends on the ability
of the cells to dynamically establish polarized networks able to
deliver structural and informational macromolecules to distinct cellular
sites. Studies
of organelle movements and transport of endogenous and viral proteins
suggest that organelle and macromolecular trafficking pathways involve
transient or stable interactions with cortical microtubule-associated endoplasmic reticulum sites (C-MERs). The observations suggest that C-MERs may function as cortical
hubs that organize cargo exchange between organelles and allow the
recruitment, assembly, and subsequently site-specific delivery of
macromolecular complexes. We propose that viruses interact with such
hubs for replication and intercellular spread.