INVESTIGADORES
PEÑA Eduardo Jose
artículos
Título:
Malachite green derivatives for two-photon RNA detection
Autor/es:
LUX, JACQUES *; PEÑA, EDUARDO *; BOLZE, FRÉDÉRIC ; HEINLEIN, MANFRED; NICOUD, JEAN-FRANÇOIS; (*) IGUAL CONTRIBUCIÓN
Revista:
CHEMBIOCHEM
Editorial:
WILEY-V C H VERLAG GMBH
Referencias:
Lugar: Weinheim; Año: 2012 vol. 13 p. 1206 - 1213
ISSN:
1439-4227
Resumen:
The design, preparation and characterisation of a library of malachite green (MG) derivatives for two-photon RNA labelling is described. Some of these MG derivatives exhibit an increased affinity for an MG-aptamer, as well as improved two-photon sensitivity when compared to the classical malachite green chloride. The underlying mechanisms and potential benefits for in vivo RNA visualisation are discussed.
