Polymeric Materials, Advances and Applications in Tissue Engineering: A Review

SOCCI MARÍA CECILIA; RODRÍGUEZ GABRIELA; OLIVA EMILIA; SHIGEKO FUSHIMI; KIYOFUMI TAKABATAKE; HITOSHI NAGATSUKA; CARMELO JOSÉ FELICE; ANDREA PAOLA RODRIGUEZ

Bioengineering

Bioengineering Editorial Office

Año: 2023 vol. 10

2306-5354

Tissue Engineering (TE) is an interdisciplinary field that encompasses materials science incombination with biological and engineering sciences. In recent years, an increase in the demand for therapeutic strategies for improving quality of life has necessitated innovative approaches to designing intelligent biomaterials aimed at the regeneration of tissues and organs. Polymeric porous scaffolds play a critical role in TE strategies for providing a favorable environment for tissue restoration and establishing the interaction of the biomaterial with cells and inducing substances. This article reviewed the various polymeric scaffold materials and their production techniques, as well as the basic elements and principles of TE. Several interesting strategies in eight main TE application areas of epithelial, bone, uterine, vascular, nerve, cartilaginous, cardiac, and urinary tissue were included with the aim of learning about current approaches in TE. Different polymer-based medical devices approved for use in clinical trials and a wide variety of polymeric biomaterials are currently available as commercial products. However, there still are obstacles that limit the clinical translation of TE implants for use wide in humans, andmuch research work is still needed in the field of regenerativemedicine.