The role of the protein Furry in the establishment of the body plan of Xenopus laevis

CERVINO, AILEN; CIRIO, MARIA CECILIA

Workshop; Embryology: Concepts and Techniques in Modern Developmental Biology; 2022

Marine Biological Laboratory

Antecedents: During early development, the animal body plan is elaborated as the result of cellular fate acquisition and coordinated gastrulation movements. The FRY microtuble binding protein (fry) geneencodes an evolutionarily conserved protein called Furry (Fry) that exhibits a wide variety of cellular functions, mainly associated with cell polarization, cell division, and morphogenesis. However, little is knownabout its role in these processes during vertebrate embryogenesis.Aim: Study the role of Fry protein in the establishment of the embryonic body plan, focusing on the morphogenetic movements of gastrulation.