INVESTIGADORES
CESCHIN Danilo Guillermo
artículos
Título:
A quality control system for profiles obtained by ChIP sequencing
Autor/es:
MENDOZA-PARRA, MA; VAN GOOL, W; MOHAMED SALEEM, M; CESCHIN, DG; GRONEMEYER, H
Revista:
NUCLEIC ACIDS RESEARCH
Editorial:
OXFORD UNIV PRESS
Referencias:
Lugar: Oxford; Año: 2013
ISSN:
0305-1048
Resumen:
The absence of quality control (QC) systems is a major obstacle for comparative analyses of genome-wide profiles generated by next generation sequencing (NGS). Here we present a bioinformatics-based approach that associates global and local QC indicators to virtually any NGS profile. This QC analysis was used to certify more than 1,600 publicly available profiles and create a database of reference QC indicators for data mining and profile comparison.
