INVESTIGADORES
DANSEY Maria Virginia
artículos
Título:
Rearrangement of 4â,5â-methylenepregnanes: a simple aproach to A-homopregnanes and 5â-methylpregnanes
Autor/es:
DI CHENNA, PABLO HECTOR; DANSEY, MARIA VIRGINIA; GHINI, ALBERTO; BURTON, GERARDO
Revista:
Arkivoc
Editorial:
ARKAT
Referencias:
Lugar: Estados Unidos; Año: 2005 vol. 2005 p. 154 - 162
ISSN:
1424-6376
Resumen:
A-homopregnanes and 5â-methylpregnanes were prepared from the easily available 3â -hydroxy-20 â -acetoxy-4 â,5 â-methylenepregnane by cationic and radical rearrangements respectively. The A-homopregnane was formed in a single step upon spontaneous rearrangement and elimination by treatment of the cyclopropyl alcohol with BF3·Et2O. The 5 â -methylpregnane was obtained by cleavage of the hydrazone of the corresponding cyclopropylketone followed by rearrangement mediated by mercury(II) hydrides.
