Editorial: Thyroid hormone actions in cancer

CAYROL F; HELENA STERLE; MONTESINOS MARIA DEL MAR

FRONTIERS IN ENDOCRINOLOGY

Frontiers Media S.A.

Año: 2023 vol. 14

1664-2392

The overall aim of this special issue is to build a better understanding of the contribution and significance of THs impact on cancer cells and on the associated antitumor immune response. The issue will focus on studies showing the influence of thyroid hormones on genetic, molecular or cellular mechanisms that are involved in tumorigenesis, cancer metabolism, tumor proliferation/survival and cancer progression. The effects of THs on the composition of the tumor microenvironment and the antitumor immune responses will also be discussed. The knowledge of the mechanisms of thyroid hormone actions in cancer could lead to the identification of new therapeutic targets or to the use of the modulation of the thyroid status to improve treatment outcomes in patients.