Characterization of persistent follicles induced by prolonged treatment with progesterone in dairy cows: An experimental model for the study of ovarian follicular cysts

DÍAZ P.U.; STANGAFERRO M.L.; GAREIS N.; SILVIA W.; MATILLER V; SALVETTI N.R.; REY F.; BARBERIS, F.; CATTANEO, L.; ORTEGA H. H.

THERIOGENOLOGY

ELSEVIER SCIENCE INC

Lugar: Amsterdam; Año: 2015

0093-691X

Cystic ovarian disease (COD) is a major factor contributing to poor reproductive efficiency of lactating dairy cows. The objective of the present study was to analyze the endocrine profile, growth dynamics and histological characteristics of persistent ovarian follicles/cysts developing in response to long-term administration of intermediate levels of progesterone. To this end, after synchronization of cows, a low dose of progesterone was administered for 5, 10 and 15 days after the expected day of ovulation in treated cows (groups P5, P10 and P15 respectively), using an intravaginal progesterone-releasing device. A significant increase in diameter was detected on day 11 of progesterone treatment and thereafter (p