INVESTIGADORES
FERNANDEZ Maria Elena
artículos
Título:
Comparison of the effectiveness between microsatellites and SNP panels for genetic identification, traceability and parentage in an inbred Angus herd
Autor/es:
FERNÁNDEZ ME *(1º AUTOR); GOSZCZYNSKI DE *(1º AUTOR); LIRÓN JP; VILLEGAS CASTAGNASSO EE; CARINO MH; RIPOLI MV; ROGBERG MUÑOZ A; POSIK DM; PERAL GARCÍA P; GIOVAMBATTISTA G
Revista:
GENETICS AND MOLECULAR BIOLOGY
Editorial:
SOC BRASIL GENETICA
Referencias:
Año: 2012 vol. 36 p. 185 - 191
ISSN:
1415-4757
Resumen:
During the last decade, microsatellites (STRs, Short Tandem Repeats) have been successfully used in animal genetic identification, such as traceability and paternity. In the last years single nucleotide polymorphisms (SNPs) have increased popularity. An efficient SNP identification system requires a marker set with enough power to identify individuals and their parents. Usually, genetic diagnostics include the analysis of related animals. In this work, the degree of information obtained through SNPs versus STRs within a consanguineous herd was compared. Thirty-six closely related Angus were genotyped for 18 STRs and 116 SNPs. Cumulative SNPs exclusion power (Q) values for paternity and sample matching (MP) resulted higher than 0.9998 and 4.32E. Between 2 and 3 SNPs per STR were needed to obtain an equivalent Q value. MP showed that 24 SNPs are equivalent to the 12 STRs ISAG (International Society for Animal Genetics) minimal recommended set. These results could provide real valuable genetic data that support the consensus SNP panel for bovine genetic identification developed by the Parentage Recording Working Group of ICAR (International Committee for Animal Recording).