INVESTIGADORES
REY Osvaldo
artículos
Título:
Human papillomavirus type 16 E7 oncoprotein represses transcription of human fibronectin
Autor/es:
REY O, LEE S, PARK NH.
Revista:
JOURNAL OF VIROLOGY
Editorial:
AMER SOC MICROBIOLOGY
Referencias:
Año: 2000 p. 4912 - 4918
ISSN:
0022-538X
Resumen:
The E7 oncoprotein encoded by human papillomavirus (HPV) type 16 repressed the transcription of fibronectin, a key component of the extracellular matrix. This repression, detected in several HPV-positive nontumorigenic and tumorigenic cell lines, was abolished when the Cys-X-X-Cys repeats in E7 were disrupted